Macular Amyloidosis
    What is macular amyloidosis?

Macular amyloidosis or friction amyloidosis are pruritic macule which are gray-brown in colour. They gradually come together in a ripped pattern and turn into a patch. It can be seen on the upper back, and sometimes on the chest, arms, and thighs. There are three main primary forms of amyloidosis namely:

  • Macular amyloidosis
  • Lichen amyloidosis
  • Nodular amyloidosis

Other form known as biphasic amyloidosis where one can see in both lichen and macular amyloidosis together on the body.

What are the causes of macular amyloidosis?

Macular amyloidosis are caused due to:

Trauma, ultra violet radiation, genetic predisposition and infectious agents. These are the few causes where one can get macular amyloidosis.

Things to Know

Medical options

  • Topical corticosteroids
  • Topical calcineurin inhibitors
  • Intralesional corticosteroids
  • Systemic retinoids
  • Systemic cyclophosphamide

Physical modalities

  • Ultraviolet (UV) B phototherapy (narrow band and broadband)
  • PUVA (psoralen with UVA) phototherapy

Surgical options

  • Dermabrasion
  • CO2 laser therapy
Age is not specified, but usually it can be seen between the age of 60-70yrs of age. Also can be seen between the age of 30-40 yrs of age.
Female patients are more prone to this condition than male patients.
  • Do not rub the affected site as it can worsen the condition
  • Take medications under the supervision of the doctor
  • Follow all the instruction as told by the doctor

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